How Can You Maintain Clean Rooms In Laboratories
Clean rooms are vital for chemical and biological laboratories. With most procedures needing a sterile environment, they’re an indispensable part of any laboratory. They’re quite hard to implement and maintain because of the stringent regulations that need to be followed.
In this infographic, we’re giving you an overview of what procedures and regulations need to be followed in clean rooms. If you’re looking for advisory services on aspects such as this, reach out to us today: https://www.kewaunee.in/contact-us.php
| Aspects to consider |
Key Pointers |
| Laboratory Layout |
- A clear workflow must be put in place
- Doors & pathways must be free of critical processes – no blockage of airflow
- Include only a single access point
- Account for all contamination risks – equipment, personnel, exit points, etc.
|
| ISO Classification |
- Must follow the International Standards Organization (ISO) classification system, ISO 14644-1
- Always best to find out the needed ISO classification before constructing the laboratory
- ISO classification can change over time, too, once the scope of work changes
- ISO 1 to ISO 9, 1 being the cleanest
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| Regular Maintenance |
- Cleaning equipment itself can be a source of contamination
- Depending on the ISO classification, you can decide what chemicals must be used to clean the space
- Special clean room friendly solvents & brooms are available
- Maintenance must be scheduled periodically
|
| Equipment Maintenance |
- Equipment can affect cleanliness either due to the space they occupy or after usage during experiments
- Technicians must clean out fume hoods and other ventilated devices regularly
- HVAC control system must be monitored for temperature, pressure, and humidity
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| Air Quality |
- Air samplers or settler plates must be used to identify the degree of contamination
- They must be checked the presence of microbial organisms based on particle size and growth on media
- They must be kept out for at least 4 hours before incubation
|
| Employee Training |
- Dress codes must be followed at all times, and PPE is mandatory
- SOPs must be present for emergencies such as spills
- Decontamination procedures are a must – cleaning with scrubbers/ showers
- Employees must be trained in using equipment such as fume hoods, etc.
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