Design Considerations For BSL III & IV Labs

In our previous post, we looked at the specific requirements of BSL-I and BSL-II laboratories. The more hazardous the material is, the more containment measures need to be implemented. 

In this infographic, we’re going to focus on the specifics of BSL-III and BSL-IV laboratories and what you need to account for before setting up your own containment level. 

At Kewaunee International, we’re the experts in understanding your requirements and which laboratory type is best suited for your work. If you’re looking for guidance on the same, contact us today:

Types of Lab Design Considerations
  • The lab must contain an anteroom & laboratory rooms
  • All doors and windows must be sealed and access-only
  • Air balance must be accounted for – should flow from low hazard areas to high hazard areas
  • Critical mechanical equipment must be present externally
  • Equipment must have its own decontamination room
  • Laboratory must be present in a restricted area – away from other office spaces
  • Floors must be impermeable to any material
  • Walls must be durable but also washable – for decontamination
  • Walls & ceiling must be painted with epoxy or acrylic paint
  • Emergency equipment must be present in each room
  • Plumbing must be airtight & furniture must also be damage-proof
  • Cabinet labs have glove boxes connected in long lines; suit labs are those in which personnel wear high-pressure suits
  • Depressurization is mandatory – from safe zones to hazardous zones
  • Bladder valves need to be placed at critical points of the enclosure
  • Bioseal doors are mandatory for these establishments 
  • Building-pressure sensors must be present at each floor level on every exterior wall closure
  • Spaces have unidirectional air flow – with double layered HEPA filters for added protection
  • All ducts must be welded to prevent any type of leakage 
  • Breathing suits with transparent face plates are mandatory
  • Emergency equipment and stations must be present within the laboratory 
  • Liquid effluent treatment system must treat liquid waste before it leaves the building

Source: Oregon State University Lab Manual; HPAC Engineering

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